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KMID : 0605820140210010001
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Korean Journal of Pediatric Infectious Diseases
2014 Volume.21 No. 1 p.1 ~ p.8
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Clinical and Laboratory Findings of the 2012 Winter Seasonal Influenza A and B Outbreak at a Single Institution
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Choi Jae-Won
Cho Hyun-Jun
Kim Hwang-Min
Hahn Seok
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Abstract
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Purpose: The aim for this study was to investigate clinical manifestation of seasonal influenza A and B during the 2012 winter season in Wonju, South Korea. Their clinical and laboratorial characteristics and effect of oseltamivir were compared and analyzed.
Methods: Children under the age of 18 years who visited the Wonju Severance Christian Hospital with fever or acute respiratory symptoms and who were diagnosed with influenza A or B by rapid antigen test from nasopharyngeal swab were selected for the study. The medical records of patients were retrospectively reviewed.
Results: Influenza A was detected in 374 patients (83.7%), and influenza B in 72 (16.6%). The incidence of influenza A was highest in February (n=186), while that of influenza B was highest in March (n=36). The most common symptoms were fever (n=434, 97.1%) and cough (n=362, 81.0%). No significant differences were observed between influenza A and B in symptoms and laboratory data. Patients who had used oseltamivir within 2 days showed statistically lower admission rate, shorter admission duration, and lower incidence of pneumonia.
Conclusion: This study found no statistical difference between influenza A and B, in symptoms, progression, and laboratorytest, but those who were treated with oseltamivir given within 2 days of the onset of fever experienced more positive outcomes.
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KEYWORD
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Influenza, Seasonal Influenza A, Seasonal Influenza B
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